An Unmet Need for Chronic Cough in IPF
Cough in IPF is often severe and difficult for practitioners to treat and there is a lack of available therapies. 1
Current Off-Label Treatments
Practitioners have tested an array of treatments to help combat cough in IPF.
Neuromodulators
No clinical trials have been conducted in IPF Chronic Cough specifically.2
Low dose steroids
While often tested, there is not substantial data to support if low dose steroids work.1
Antitussive therapy
Usually has no impact on IPF cough.1
Speech therapy
No clinical trials have been conducted in IPF Chronic Cough specifically.2
Neuromodulators
No clinical trials have been conducted in IPF Chronic Cough specifically.2
Antitussive therapy
Usually has no impact on IPF cough.1
Low dose steroids
While often tested, there is not substantial data to support if low dose steroids work.1
Speech therapy
No clinical trials have been conducted in IPF Chronic Cough specifically.2
While searching for relief from chronic cough, the trial and error of testing different therapies can lead patients and clinicians to feel frustrated.1
There are currently no approved therapies for IPF patients suffering from chronic cough.
Looking for helpful tips for managing your patients’ cough? Action for Pulmonary Fibrosis has put together this list here.
Clinical Research
Research is currently being conducted on possible therapies for chronic cough in IPF. Your patients can join a clinical trial of an investigational therapy by accessing them through clinicaltrials.gov
References
1. Hope-Gill BD, et al., Am J Respir Crit Care Med, 2003. doi: 10.1164/rccm.200304-597OC
2. Wakwaya Y, et al., Chest, 2021. doi: 10.1016/j.chest.2021.05.071
Trevi Therapeutics New Haven, CT.
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